Stage independent chloroquine resistance and chloroquine toxicity revealed via spinning disk confocal microscopy
نویسندگان
چکیده
منابع مشابه
variation of the chloroquine resistance transporter (crt) gene in chloroquine-resistant and chloroquine-sensitive plasmodium berghei
background: the emergence and spread of chloroquine resistant plasmodium falciparum in the world stimulated some investigators to consider different aspects of chloroquine resistance in human and rodent plasmodia . using animal plasmodia , particularly primate and rodent plasmodia can be useful model for human plasmodia studies. in this study we have tried to consider and compare the sequence ...
متن کاملChloroquine resistance in malaria.
Malaria continues to pose a challenge in view of its resurgence and problem of drug resistance. The chloroquine resistance in P. falciparum was first detected in Thailand in 1962(1) and in India in 1973(2). The extent of problem of chloroquine resistance in P. falciparum is increasing every year. Chloroquine resistance in P. falciparum has already been found in twelve different states and Union...
متن کامل[Retinal toxicity following chloroquine therapy].
CASE REPORT Two cases of bilateral ocular toxicity following chloroquine therapy in two women with systemic lupus erythematosus are presented. DISCUSSION Retinal toxicity due to chloroquine is an uncommon iatrogenic disease. It is dose-dependent. New cases are still being described despite the application of ophthalmic screening techniques.
متن کاملVariation of the Chloroquine Resistance Transporter (Crt) Gene in Chloroquine-Resistant and Chloroquine-Sensitive Plasmodium berghei
Background: The emergence and spread of chloroquine resistant Plasmodium falciparum in the world stimulated some investigators to consider different aspects of chloroquine resistance in human and rodent Plasmodia. Using animal Plasmodia, particularly primate and rodent Plasmodia can be useful model for human Plasmodia studies. In this study we have tried to consider and compare the sequence of ...
متن کاملMalaria: Dissecting chloroquine resistance
The malaria parasite's development of resistance to the drug chloroquine is a major threat to world health. A protein likely to be involved in chloroquine resistance has recently been identified; this discovery is important, but raises as many questions as it answers.
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ژورنال
عنوان ژورنال: Molecular and Biochemical Parasitology
سال: 2008
ISSN: 0166-6851
DOI: 10.1016/j.molbiopara.2007.12.014